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Pathology Outlines Melanotic macule Pigmented macule on the mandibular gingiva (a, case 1), affecting the Download Scientific Diagram Pigmented Lesions of the Oral Cavity Geeky Medics Smokers melanosis . Oral pigmentation seen in heavy smokers . Investigations have shown ability of melanin to bind to noxious substances. . Exposure to polycyclic amines ( Nicotine & benzpyrene) has shown Multifocal pigmentation of the oral mucosa The Journal of the American Dental Association Diagnosis of oral pigmentations and malignant transformations ScienceDirect
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